The Indian Institute of Soybean Research, Indore (ICAR-IISR) now National Soyabean Research Institute is an agricultural research institution located in Indore (Madhya Pradesh, India) that focuses on basic and strategic research on soybeans.

IISR was established under the aegis of the Indian Council of Agricultural Research (ICAR), a government agency. It conducts agricultural research on soybean breeding, improvement, pathology, and value additions using soybean. The IISR coordinates and facilitates the conduct of soybean research at the national level through the All India Coordinated Research Projects on soybean (AICRP on Soybean) as well as providing links between various national and international agencies